Is the hepatitis B vaccine less effective in people who have celiac disease?
Numerous research studies have found that the hepatitis B vaccine is less likely to be effective in individuals with celiac disease. * Some research shows that people with well-controlled celiac disease and compliant with a gluten-free diet do not have this issue.
No standard recommendation exists to address this situation. Each individual case can vary depending on when the vaccine was received relative to initiating a gluten-free diet and achieving good celiac disease control. The best course of action is to discuss the situation with a personal physician and healthcare team to determine whether re-vaccination is needed.
*Note that this interference with the effectiveness of a vaccine due to celiac disease does not apply to other vaccines; only to the hepatitis B vaccine.
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